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KMID : 0614620090530040235
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Korean Journal of Gastroenterology
2009 Volume.53 No. 4 p.235 ~ p.238
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Is End Stage Renal Disease a Poor Prognosis Factor of Ischemic Colitis?
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Ahn Seong-Eun
Lee Hang-Lak
Cho Seung-Chul
Yoon Jai-Hoon
Lee Oh-Young
Yoon Byung-Chul
Choi Ho-Soon
Hahm Joon-Soo
Lee Min-Ho
Lee Dong-Hoo
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Abstract
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Background and Aims: In general, ischemic colitis has a very good prognosis. However, there are a lot of controversies in relation to the prognostic factors. The aim of this study was to evaluate risk factors of severe ischemic colitis.
Methods: A retrospective study was undertaken of patients with ischemic colitis hospitalized at the Hanyang University Hospital during the interval 2004-2006. Patients were divided into two groups: those with mild course and those with severe course which led to operation, systemic inflammatory response syndrome, or death.
Results: A total of 41 cases (M/F=13/28, mean age=63.8 years) of biopsy proven ischemic colitis were included, of which 31 (75.6%) had a mild course and 10 (24.4%) a severe course. Coexisting medical diseases of patients were hypertension (n=24), diabetes (n=14), end-stage renal disease (n=11), cardiovascular disease (n=5), and malignancy (n=5). Male (p=0.049), alcoholics (p=0.025), end-stage renal disease (p=0.013), LDH (p=0.002), CRP (p=0.014), and peritoneal irritation sign (p=0.001) were the significant risk factors of severe ischemic colitis in univariate analysis. In multivariate logistic regression analysis, end-stage renal disease (p=0.026) was the only significant risk factor of severe ischemic colitis.
Conclusions: Careful attention must be paid to end-stage renal disease patients having ischemic colitis.
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KEYWORD
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Ischemic colitis, End stage renal disease
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